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In long-term studies (at least 48 weeks), both the magnitude of weight gain and the proportion of olanzapine-treated patients who had clinically significant weight gain were greater than in short-term studies.
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This treatment approach relies on case management and focuses on making sense of emotionally difficult moments by considering the interpersonal context for feelings.
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The mechanism by which olanzapine causes serum aminotransferase elevations is not known.
Most important, by emphasizing drug treatment, psychiatry became the darling of the pharmaceutical industry, which soon made its gratitude tangible.
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This may explain the low incidence of extrapyramidal side effects with olanzapine usually associated with the typical antipsychotics.
FDA is unable to exclude the possibility that the deaths were caused by rapid, but delayed, entry of the drug into the bloodstream following intramuscular injection.
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Because of the subjective nature of psychiatric diagnosis, the ease with which diagnostic boundaries can be expanded, the seriousness of the side effects of psychoactive drugs, and the pervasive influence of their manufacturers, I believe doctors should be prohibited from prescribing psychoactive drugs off-label, just as companies are prohibited from marketing them off-label.
If elect to use olanzapine for extended periods, periodically reevaluate the long-term usefulness for the individual patient.
Zyprexa works by blocking receptors that dopamine act on to prevent the over-activity of dopamine and help control schizophrenia.
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It should be noted that although Zyprexa is classified as an A-typical antipsychotic, it is also used as a mood stabilizer in patients with Bipolar Disorder.
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In placebo-controlled olanzapine clinical studies (up to 12 weeks), changes from normal to high in prolactin concentrations were observed in 30% of adults treated with olanzapine as compared to 10.
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Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as olanzapine have an increased chance of death during treatment.
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On April 16, 2004, the first nationwide Zyprexa class action lawsuit was filed against Eli Lilly, the makers of this atypical antipsychotic prescription drug.
Seroquel may cause you to have high blood sugar (hyperglycemia).
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Patients with hepatic complications are usually given a vitamin K supplement.
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Zyprexa side effects in children and adults alike are physical and mental, when you have been taking an atypical antipsychotic medication for a long period of time; your body and mind both start to depend on it which leads to another major side effect: Zyprexa withdrawal upon discontinuation.
If the physcian who put me on this drug would have told me this would happen, I would have never consented to go on the medication!
It may also be useful in the treatment of mania that is non-responsive to medications.
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